Doktor Bilgileri

Ali Gharavi

Nefroloji
United States, New York

Subspecialty :Chronic Glomerular Diseases

Dr. Ali Gharavi, a leading kidney disease researcher, is chief of the division of nephrology at NewYork-Presbyterian/Columbia University Medical Center. Dr. Gharavi, also an associate professor of medicine at Columbia University College of Physicians and Surgeons and director of its renal physiology and pathophysiology course, joined NewYork-Presbyterian/Columbia in 2003.“My objective is to bring personalized genomic nephrology from the laboratory into patient care,” says Dr. Gharavi. “Owing to the recent progress in genomic technologies, we now have the opportunity to make a precise genetic diagnosis for many patients and individualize care based on the specific molecular mechanism of disease.” The principal investigator on four current projects funded by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health and the New York State Empire Clinical Research Investigator Program, Dr. Gharavi has specific interests in the genetics of kidney disease, including IgA nephropathy and congenital abnormalities of the kidney and urinary tract. IgA nephropathy is a kidney disorder that occurs when IgA—an antibody that helps the body fight infections—settles in the kidneys, which can cause the kidneys to leak blood and sometimes protein in the urine. It can eventually lead to kidney failure.Dr. Gharavi’s work has identified multiple regions of the genome that confer risk of IgA nephropathy and has yielded novel insight into the mechanisms of kidney injury underlying the condition. His other research includes the genetic causes of congenital abnormalities of the kidney and the urinary tract, the most common cause of kidney failure in children, for which he has described several new genetic mutations. Dr. Gharavi is a member of the American Society of Nephrology, International Society of Nephrology, and American Society of Human Genetics. He is the author of 63 peer-reviewed publications in high-impact journals including Nature, Nature Genetics and the New England Journal of Medicine, sits on the editorial boards of the Journal of the American Society of Nephrology and Kidney International, and has been a guest editor of PLoS Genetics. He was a recipient of the Judson Daland Prize for Outstanding Clinical Investigation from the American Philosophical Society and the National Kidney Foundation Clinical Scientist Award and was elected to the American Society of Clinical Investigation.After receiving his medical degree from George Washington University, Dr. Gharavi completed his residency at Mount Sinai Medical Center and fellowships in hypertension and nephrology, also at Mount Sinai. He then completed a postdoctoral fellowship in genetics at Yale University School of Medicine. He previously held academic appointments at Yale University School of Medicine and Mount Sinai School of Medicine and hospital appointments at Mount Sinai Hospital.